Defyne can treat deep nasolabial folds to ensure appearance is smoothed out. Restylane Defyne is a soft-gel filler containing 0.3% lidocaine to increase optimum comfort of treatment for the patient. A more higher volume lifting result to iron out deep nasolabial folds. This product contains the active ingredient cross linked, non- animal based Butanediol Diglycidyl Ether (BDDE). Optimal Balance Technology allows these fillers to integrate smoothly into the skin, giving a higher acceptance rate by the patient�s skin. OBT ensures an optimal balance between the level of cross-linking and gel calibration that exists due to an equilibrium concentration of hyaluronic acid Individual�s self-esteem and confidence are increased as a result of lines and wrinkles instantly being smoothed away. Hyaluronic Acid (non-cross linked) containing 0,3% lidocaine. 1 x 1.0ml syringes. Injected into the mid-deep layer of the skin dermis, Restylane Defyne can be used to reduce the following: Deep wrinkles and lines, Nasolabial folds, Marionette lines. Results are safe and instant from the first treatment. The overall effects will last from 6 to 9 months and even up to one year depending on the individuals skin type factors, such as age, lifestyle and technique used.