Plinest One is an injectable skin booster from Mastelli’s New Cellular Matrix (NCM®) range, designed to restore skin quality and slow down the visible signs of ageing. It combines polynucleotides (PN-HPT®) – DNA fragments that stimulate cell repair and regeneration – with hyaluronic acid, which provides deep hydration and plumping. This dual-action formula helps to: Improve skin elasticity and firmness Reduce fine lines and wrinkles Enhance hydration and radiance Support tissue repair and collagen production Plinest One is suitable for patients showing early to moderate signs of ageing or skin damage, and it can be used on the face, neck, décolletage, and hands. Treatments are typically carried out in a course for long-lasting rejuvenation.